Amoxicillin oral provocation challenge in a primary care clinic: a descriptive analysis

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Figure 1:
Protocol for eligibility for oral provocation challenge, using the self-reported results from the patient intake form (Appendix 2, available at www.cmajopen.ca/content/9/2/E394/suppl/DC1).

Table 1:

World Allergy Organization Subcutaneous Immunotherapy Systemic Reaction Grading System (20)

Grade	Symptoms or signs
1	Cutaneous, upper respiratory (rhinitis, throat clearing, cough), conjunctival or other (nausea, metallic taste or headache)
2	More than 1 organ system, lower respiratory, gastrointestinal, or uterine cramps
3	Lower respiratory or upper respiratory (laryngeal, uvula or tongue edema)
4	Respiratory failure or cardiovascular (hypotension)
5	Death

Table 2:

Demographic characteristics of patients who were included in the study

Characteristic	No. (%) of included patients^*^† n = 99
Sex
Male	27 (27)
Female	72 (73)
Age, yr; mean ± SD (n = 98)	28.3 ± 21.1
Age < 18 yr	41 (42)
Mean	8.0 ± 4.1
Age ≥ 18 yr	57 (58)
Mean	42.9 ± 15.5
Wait time, d; mean ± SD (n = 97)	59.0 ± 69.8
Wait time < 45 d	53 (54)
Mean	18.0 ± 13.8
Wait time ≥ 45 d	46 (44)
Mean	108.4 ± 78.0
Family history of penicillin allergy (n = 97)
No	80 (83)
Yes	17 (17)
Personal history of immediate reaction to penicillin (n = 90)
No	81 (90)
Yes	9 (10)

Note: SD = standard deviation.
↵* Unless specified otherwise.
↵† Observations with missing information on a characteristic were excluded from the relevant analysis.