Acute diabetes complications across transition from pediatric to adult care in Ontario and Newfoundland and Labrador: a population-based cohort study

Rayzel Shulman; Longdi Fu; John C. Knight; Astrid Guttmann; Roger Chafe

doi:10.9778/cmajo.20190019

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Figure 1:
Flow diagram showing participant selection.

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Table 1:

Baseline characteristics of youth with diabetes in Ontario and Newfoundland and Labrador on their 17th birthday

Characteristic	No. (%) of participants^*
Characteristic	Ontario n = 2525	Newfoundland and Labrador n = 93
Male sex	1309 (51.8)	47 (50.5)
Duration of diabetes, yr
Mean ± SD	7.4 ± 3.8	7.9 ± 3.8
Median (IQR)	6.7 (4.3–10.2)	7.6 (4.5–11.0)
Deprivation quintile^†
1 (least deprived)	702 (27.8)	13 (14.0)
2	587 (23.2)	13 (14.0)
3	504 (20.0)	15 (16.1)
4	364 (14.4)	13 (14.0)
5 (most deprived)	326 (12.9)	39 (41.9)
Missing	42 (1.7)	< 6^‡
Rurality
Not census metropolitan area (rural)	387 (15.3)	59 (63.4)
Census metropolitan area (urban)	2138 (84.7)	34 (36.6)

Note: IQR = interquartile range, SD = standard deviation.
↵* Except where noted otherwise.
↵† Based on the 2006 Canadian Marginalization Index. (18)
↵‡ Added to quintile 5 owing to small cell size.

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Table 2:

Standardized rates of and proportion of participants with any hospital admission, admissions related to diabetes and admissions related to diabetic ketoacidosis across transition age, standardized according to material deprivation

Variable	Ontario; age, yr		Newfoundland and Labrador; age, yr

	15–17	18–20	15–17	18–20
All admissions

Events/100 person-years (95% CI)	23.8 (22.6–25.0)	25.4 (24.1–26.6)	20.9 (15.0–26.8)	22.6 (16.5–28.7)

Rate, % (95% CI)	32.7 (30.8–34.7)	34.0 (32.1–36.0)	32.0 (21.7–42.3)	31.8 (21.5–42.1)

Diabetes-related admissions

Events/100 person-years (95% CI)	13.5 (12.6–14.4)	14.4 (13.5–15.3)	11.4 (7.0–15.8)	10.5 (6.4–14.6)

Rate, % (95% CI)	19.0 (17.3–20.6)	18.8 (17.2–20.4)	23.0 (13.7–32.3)	19.4 (10.7–28.1)

Diabetic-ketoacidosis–related admissions

Events/100 person-years (95% CI)	10.6 (9.8–11.4)	12.7 (11.8–13.6)	7.7 (4.0–11.4)	8.8 (5.1–12.6)

Rate, % (95% CI)	14.9 (13.4–16.4)	17.7 (16.1–19.3)	17.3 (8.8–25.9)	18.9 (10.2–27.5)