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Research

Postpartum self-inflicted injury, suicide, assault and homicide in relation to immigrant status in Ontario: a retrospective population-based cohort study

Simone N. Vigod, Serena Arora, Marcelo L. Urquia, Cindy-Lee Dennis, Kinwah Fung, Sophie Grigoriadis and Joel G. Ray
April 12, 2019 7 (2) E227-E235; DOI: https://doi.org/10.9778/cmajo.20180178
Simone N. Vigod
Women’s College Hospital and Research Institute (Vigod, Arora); ICES (Vigod, Urquia, Fung); Department of Psychiatry (Vigod, Grigoriadis, Ray), University of Toronto, Toronto, Ont.; Department of Community Health Sciences (Urquia), Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Man.; Li Ka Shing Knowledge Institute (Dennis, Ray), St. Michael’s Hospital; Faculty of Nursing (Dennis), University of Toronto; Department of Psychiatry (Grigoriadis), Sunnybrook Health Sciences Centre; Department of Medicine (Ray), University of Toronto, Toronto, Ont.
MD MSc
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Serena Arora
Women’s College Hospital and Research Institute (Vigod, Arora); ICES (Vigod, Urquia, Fung); Department of Psychiatry (Vigod, Grigoriadis, Ray), University of Toronto, Toronto, Ont.; Department of Community Health Sciences (Urquia), Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Man.; Li Ka Shing Knowledge Institute (Dennis, Ray), St. Michael’s Hospital; Faculty of Nursing (Dennis), University of Toronto; Department of Psychiatry (Grigoriadis), Sunnybrook Health Sciences Centre; Department of Medicine (Ray), University of Toronto, Toronto, Ont.
BA
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Marcelo L. Urquia
Women’s College Hospital and Research Institute (Vigod, Arora); ICES (Vigod, Urquia, Fung); Department of Psychiatry (Vigod, Grigoriadis, Ray), University of Toronto, Toronto, Ont.; Department of Community Health Sciences (Urquia), Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Man.; Li Ka Shing Knowledge Institute (Dennis, Ray), St. Michael’s Hospital; Faculty of Nursing (Dennis), University of Toronto; Department of Psychiatry (Grigoriadis), Sunnybrook Health Sciences Centre; Department of Medicine (Ray), University of Toronto, Toronto, Ont.
PhD MSc
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Cindy-Lee Dennis
Women’s College Hospital and Research Institute (Vigod, Arora); ICES (Vigod, Urquia, Fung); Department of Psychiatry (Vigod, Grigoriadis, Ray), University of Toronto, Toronto, Ont.; Department of Community Health Sciences (Urquia), Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Man.; Li Ka Shing Knowledge Institute (Dennis, Ray), St. Michael’s Hospital; Faculty of Nursing (Dennis), University of Toronto; Department of Psychiatry (Grigoriadis), Sunnybrook Health Sciences Centre; Department of Medicine (Ray), University of Toronto, Toronto, Ont.
PhD
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Kinwah Fung
Women’s College Hospital and Research Institute (Vigod, Arora); ICES (Vigod, Urquia, Fung); Department of Psychiatry (Vigod, Grigoriadis, Ray), University of Toronto, Toronto, Ont.; Department of Community Health Sciences (Urquia), Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Man.; Li Ka Shing Knowledge Institute (Dennis, Ray), St. Michael’s Hospital; Faculty of Nursing (Dennis), University of Toronto; Department of Psychiatry (Grigoriadis), Sunnybrook Health Sciences Centre; Department of Medicine (Ray), University of Toronto, Toronto, Ont.
MSc
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Sophie Grigoriadis
Women’s College Hospital and Research Institute (Vigod, Arora); ICES (Vigod, Urquia, Fung); Department of Psychiatry (Vigod, Grigoriadis, Ray), University of Toronto, Toronto, Ont.; Department of Community Health Sciences (Urquia), Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Man.; Li Ka Shing Knowledge Institute (Dennis, Ray), St. Michael’s Hospital; Faculty of Nursing (Dennis), University of Toronto; Department of Psychiatry (Grigoriadis), Sunnybrook Health Sciences Centre; Department of Medicine (Ray), University of Toronto, Toronto, Ont.
MD PhD
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Joel G. Ray
Women’s College Hospital and Research Institute (Vigod, Arora); ICES (Vigod, Urquia, Fung); Department of Psychiatry (Vigod, Grigoriadis, Ray), University of Toronto, Toronto, Ont.; Department of Community Health Sciences (Urquia), Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Man.; Li Ka Shing Knowledge Institute (Dennis, Ray), St. Michael’s Hospital; Faculty of Nursing (Dennis), University of Toronto; Department of Psychiatry (Grigoriadis), Sunnybrook Health Sciences Centre; Department of Medicine (Ray), University of Toronto, Toronto, Ont.
MD MSc
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    Figure 1:

    Risk of self-inflicted injury (self-harm or suicide) and injury inflicted by others (assault or homicide), by duration of residence and by refugee status, restricted to immigrants to Canada. Note: Relative risks (RRs) are adjusted for maternal age and parity. CI = confidence interval.

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    Figure 2:

    Risks of (A) self-inflicted injury (self-harm or suicide) and (B) injury inflicted by others (assault or homicide) among immigrant women, comparing those from 19 different countries to women from India. Note: Hazard ratios (HRs) are adjusted for maternal age, parity, duration of residence and refugee status. CI = confidence interval.

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    Table 1:

    Baseline characteristics of immigrant and nonimmigrant women who gave birth in Ontario during the study period

    CharacteristicNo. (%) of women*
    Immigrants
    n = 327 279
    Nonimmigrants
    n = 942 502
    Demographic
     Age, mean ± SD, yr30.5 ± 5.229.7 ± 5.6
     Primiparous141 131 (43.1)435 940 (46.3)
     Lowest neighbourhood income quintile112 624 (34.4)175 588 (18.6)
    Maternal morbidity within 2 yr before the index birth
     Diabetes mellitus before or in pregnancy6445 (2.0)16 057 (1.7)
     Hypertension before or in pregnancy6276 (1.9)26 657 (2.8)
     Health care resource utilization bands 4 and 5 (highest)233 840 (71.4)638 345 (67.7)
    Psychiatric morbidity within 2 yr before the index birth
     Mood disorder7372 (2.3)46 849 (5.0)
     Psychotic disorder680 (0.2)2929 (0.3)
     Substance or alcohol use disorder1613 (0.5)24 966 (2.6)
     Primary care physician visit for a psychiatric disorder75 978 (23.2)271 515 (28.8)
     Psychiatrist visit5518 (1.7)34 413 (3.7)
     Psychiatric hospital admission532 (0.2)4358 (0.5)
     Deliberate self-harm2588 (0.8)20 396 (2.2)
    Obstetrical and perinatal indicators at the index birth
     Preterm birth < 37 wk gestation21 594 (6.6)68 637 (7.3)
     Birth weight, mean ± SD, g3282 ± 5573410 ± 584
     Cesarean delivery92 094 (28.1)258 841 (27.5)
     Neonatal morbidity
      Respiratory distress syndrome3724 (1.1)14 216 (1.5)
      Seizure949 (0.3)3583 (0.4)
      Sepsis4144 (1.3)14 094 (1.5)
      Intraventricular hemorrhage1745 (0.5)5490 (0.6)
      Persistent fetal circulation893 (0.3)3172 (0.3)
      Congenital/neonatal infection1219 (0.4)1219 (0.4)
      Neonatal intensive care unit admission45 976 (14.0)121 434 (12.9)
    Infant mortality < 365 d of the index birth, no. (rate)1227 (3.8 per 1000)3276 (3.5 per 1000)
    • Note: SD = standard deviation.

    • ↵* Unless specified otherwise.

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    Table 2:

    Risk of self-inflicted injury (self-harm or suicide) and injury inflicted by others (assault or homicide), comparing 327 279 immigrant women and 942 502 nonimmigrant women who gave birth in Ontario during the study period

    VariableSelf-inflicted injuryInjury inflicted by others
    No. with the outcome (rate per 1000 births)Crude RR (95% CI)Adjusted RR* (95% CI)No. with the outcome (rate per 1000 births)Crude RR (95% CI)Adjusted RR* (95% CI)
    Nonimmigrant status1199 (1.27)1.00 (reference)1.00 (reference)2710 (2.88)1.00 (reference)1.00 (reference)
    Immigrant status240 (0.73)0.58 (0.50–0.67)0.91 (0.78–1.04)360 (1.10)0.38 (0.34–0.43)0.57 (0.51–0.64)
    Maternal age, yr0.86 (0.85–0.87)0.81 (0.80–0.81)
    No. of previous births1.44 (1.39–1.51)1.64 (1.59–1.68)
    Maternal income quintile
     1, 2 or 3 (lower)1.00 (reference)1.00 (reference)
     4 or 5 (higher)0.86 (0.76–0.98)0.61 (0.56–0.68)
    Resource utilization band
     1, 2 or 3 (lower)1.00 (reference)1.00 (reference)
     4 or 5 (higher)0.88 (0.79–0.98)1.04 (0.96–1.12)
    Prior maternal psychiatric diagnosis
     No1.00 (reference)1.00 (reference)
     Yes7.01 (6.25–7.86)3.55 (3.26–3.86)
    • Note: CI = confidence interval, RR = relative risk.

    • ↵* Adjusted for maternal age, parity, income quintile, resource utilization band and prior maternal psychiatric diagnosis.

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Postpartum self-inflicted injury, suicide, assault and homicide in relation to immigrant status in Ontario: a retrospective population-based cohort study
Simone N. Vigod, Serena Arora, Marcelo L. Urquia, Cindy-Lee Dennis, Kinwah Fung, Sophie Grigoriadis, Joel G. Ray
Apr 2019, 7 (2) E227-E235; DOI: 10.9778/cmajo.20180178

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Postpartum self-inflicted injury, suicide, assault and homicide in relation to immigrant status in Ontario: a retrospective population-based cohort study
Simone N. Vigod, Serena Arora, Marcelo L. Urquia, Cindy-Lee Dennis, Kinwah Fung, Sophie Grigoriadis, Joel G. Ray
Apr 2019, 7 (2) E227-E235; DOI: 10.9778/cmajo.20180178
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