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Research

Quality-related events reported by community pharmacies in Nova Scotia over a 7-year period: a descriptive analysis

Adrian Boucher, Certina Ho, Neil MacKinnon, Todd A. Boyle, Andrea Bishop, Paola Gonzalez, Christopher Hartt and James R. Barker
December 18, 2018 6 (4) E651-E656; DOI: https://doi.org/10.9778/cmajo.20180090
Adrian Boucher
Leslie Dan Faculty of Pharmacy (Boucher, Ho), University of Toronto; Institute for Safe Medication Practices Canada (Boucher, Ho), Toronto, Ont.; James L. Winkle College of Pharmacy (MacKinnon), University of Cincinnati, Cincinnati, OH; Gerald Schwartz School of Business (Boyle), St. Francis Xavier University, Antigonish, NS; IWK Health Centre (Bishop); Rowe School of Business (Gonzalez, Barker), and Department of Business and Social Science (Hartt), Dalhousie University, Halifax, NS
BSc PharmD
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Certina Ho
Leslie Dan Faculty of Pharmacy (Boucher, Ho), University of Toronto; Institute for Safe Medication Practices Canada (Boucher, Ho), Toronto, Ont.; James L. Winkle College of Pharmacy (MacKinnon), University of Cincinnati, Cincinnati, OH; Gerald Schwartz School of Business (Boyle), St. Francis Xavier University, Antigonish, NS; IWK Health Centre (Bishop); Rowe School of Business (Gonzalez, Barker), and Department of Business and Social Science (Hartt), Dalhousie University, Halifax, NS
BScPhm PhD
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Neil MacKinnon
Leslie Dan Faculty of Pharmacy (Boucher, Ho), University of Toronto; Institute for Safe Medication Practices Canada (Boucher, Ho), Toronto, Ont.; James L. Winkle College of Pharmacy (MacKinnon), University of Cincinnati, Cincinnati, OH; Gerald Schwartz School of Business (Boyle), St. Francis Xavier University, Antigonish, NS; IWK Health Centre (Bishop); Rowe School of Business (Gonzalez, Barker), and Department of Business and Social Science (Hartt), Dalhousie University, Halifax, NS
MSc(Pharm) PhD
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Todd A. Boyle
Leslie Dan Faculty of Pharmacy (Boucher, Ho), University of Toronto; Institute for Safe Medication Practices Canada (Boucher, Ho), Toronto, Ont.; James L. Winkle College of Pharmacy (MacKinnon), University of Cincinnati, Cincinnati, OH; Gerald Schwartz School of Business (Boyle), St. Francis Xavier University, Antigonish, NS; IWK Health Centre (Bishop); Rowe School of Business (Gonzalez, Barker), and Department of Business and Social Science (Hartt), Dalhousie University, Halifax, NS
PhD
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Andrea Bishop
Leslie Dan Faculty of Pharmacy (Boucher, Ho), University of Toronto; Institute for Safe Medication Practices Canada (Boucher, Ho), Toronto, Ont.; James L. Winkle College of Pharmacy (MacKinnon), University of Cincinnati, Cincinnati, OH; Gerald Schwartz School of Business (Boyle), St. Francis Xavier University, Antigonish, NS; IWK Health Centre (Bishop); Rowe School of Business (Gonzalez, Barker), and Department of Business and Social Science (Hartt), Dalhousie University, Halifax, NS
MHSA PhD
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Paola Gonzalez
Leslie Dan Faculty of Pharmacy (Boucher, Ho), University of Toronto; Institute for Safe Medication Practices Canada (Boucher, Ho), Toronto, Ont.; James L. Winkle College of Pharmacy (MacKinnon), University of Cincinnati, Cincinnati, OH; Gerald Schwartz School of Business (Boyle), St. Francis Xavier University, Antigonish, NS; IWK Health Centre (Bishop); Rowe School of Business (Gonzalez, Barker), and Department of Business and Social Science (Hartt), Dalhousie University, Halifax, NS
MASc PhD
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Christopher Hartt
Leslie Dan Faculty of Pharmacy (Boucher, Ho), University of Toronto; Institute for Safe Medication Practices Canada (Boucher, Ho), Toronto, Ont.; James L. Winkle College of Pharmacy (MacKinnon), University of Cincinnati, Cincinnati, OH; Gerald Schwartz School of Business (Boyle), St. Francis Xavier University, Antigonish, NS; IWK Health Centre (Bishop); Rowe School of Business (Gonzalez, Barker), and Department of Business and Social Science (Hartt), Dalhousie University, Halifax, NS
PhD
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James R. Barker
Leslie Dan Faculty of Pharmacy (Boucher, Ho), University of Toronto; Institute for Safe Medication Practices Canada (Boucher, Ho), Toronto, Ont.; James L. Winkle College of Pharmacy (MacKinnon), University of Cincinnati, Cincinnati, OH; Gerald Schwartz School of Business (Boyle), St. Francis Xavier University, Antigonish, NS; IWK Health Centre (Bishop); Rowe School of Business (Gonzalez, Barker), and Department of Business and Social Science (Hartt), Dalhousie University, Halifax, NS
MA PhD
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Article Figures & Tables

Tables

    • View popup
    Table 1:

    Pharmacy characteristics

    CharacteristicNo. (%) of pharmacies
    n = 301
    Type of pharmacy*
     Chain166 (55.1)
     Banner111 (36.9)
     Independent24 (8.0)
    Population served by the pharmacy
     < 100031 (10.3)
     1000–499970 (23.3)
     5000–49 999145 (48.2)
     50 000–99 99916 (5.3)
     > 100 00039 (13.0)
    • ↵* Chain pharmacies are typically directed by a corporate office, with respect to its professional programs, marketing, ordering, etc. Banner pharmacies are independently owned pharmacies that are affiliated with a central office; they pay fees for the banner’s benefit in centralized buying, marketing and professional programs. Independent pharmacies are not affiliated with any corporately run chains or banners. The owner of an independent pharmacy has complete control over the business (e.g., ordering and marketing strategies).

    • View popup
    Table 2:

    Quality-related events reported by patient outcome

    Event reached patientPatient outcomeNo. (%)Harm QRE
    NoNo error (i.e., near miss)80 488 (82.0)No
    YesNo harm16 681 (17.0)No
    YesMild harm839 (0.86)Yes
    YesModerate harm80 (0.1)Yes
    YesSevere harm7 (0.00)Yes
    YesDeath2 (0.00)Yes
    Total98 097 (100)
    • Note: QRE = quality-related event.

    • View popup
    Table 3:

    Total number of QREs, number of harm QREs and proportion of harm QREs for each medication system stage

    StageNo. (%)% Harm QREs*
    QREsHarm QREs*
    Prescribing10 658 (9.0)159 (10.6)1.5
    Prescription order entry69 856 (58.7)411 (27.4)0.6
    Prescription preparation/dispensing34 859 (29.3)571 (38.1)1.6
    Administration2167 (1.8)228 (15.2)10.5
    Monitoring/follow-up704 (0.6)90 (6.0)12.8
    Not applicable743 (0.6)39 (2.6)5.2
    Total118 987† (100)1498† (100)–
    • Note:QRE = quality related event.

    • ↵* Harm QREs are associated with a patient outcome of mild harm, moderate harm, severe harm or death (Table 2).

    • ↵† The reporter can select multiple options for “Medication System Stages Involved” field; hence the total number of QREs and the number of QREs with harm are greater than those shown in Table 2.

    • View popup
    Table 4:

    Total number of QREs, number of harm QREs and proportion of harm QREs for each type

    TypeNo. (%) of QREsNo. (%) of harm QREs*Proportion of harm QREs*, %
    Incorrect dose or frequency25 089 (25.6)254 (27.4)1.0
    Incorrect quantity19 619 (20.0)19 (2.0)0.1
    Incorrect drug13 951 (14.2)185 (19.9)1.3
    Incorrect strength or concentration10 508 (10.7)187 (20.2)1.8
    Incorrect prescriber8454 (8.6)0 (0)0.0
    Incorrect patient5685 (5.8)32 (3.4)0.6
    Incorrect duration of treatment5048 (5.1)18 (1.9)0.4
    Incorrect dosage form or formulation (including not splitting tablets as per patient’s request)3281 (3.3)32 (3.4)1.0
    Omitted medication or dose1919 (2.0)58 (6.233.0
    Incorrect route of administration1121 (1.1)7 (0.8)0.6
    Incorrect storage857 (0.9)3 (0.3)0.4
    Incorrect third-party billing803 (0.8)1 (0.1)0.1
    Drug therapy problem — drug–drug/OTC/natural health product interaction506 (0.5)19 (2.0)3.8
    Drug therapy problem — documented allergy447 (0.5)31 (3.3)6.9
    Drug therapy problem — contraindication356 (0.4)12 (1.3)3.4
    Expired medication191 (0.2)9 (1.0)4.7
    Drug therapy problem — adverse drug reaction188 (0.2)56 (6.0)29.8
    Drug therapy problem — drug–disease interaction63 (0.1)3 (0.3)4.8
    Drug therapy problem — drug–food interaction11 (0.0)2 (0.2)18.2
    Total98 097 (100)928 (100)–
    • Note: OTC = over the counter, QRE = quality-related event.

    • ↵* Harm QREs are associated with a patient outcome of mild harm, moderate harm, severe harm or death (Table 2).

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Quality-related events reported by community pharmacies in Nova Scotia over a 7-year period: a descriptive analysis
Adrian Boucher, Certina Ho, Neil MacKinnon, Todd A. Boyle, Andrea Bishop, Paola Gonzalez, Christopher Hartt, James R. Barker
Oct 2018, 6 (4) E651-E656; DOI: 10.9778/cmajo.20180090

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Quality-related events reported by community pharmacies in Nova Scotia over a 7-year period: a descriptive analysis
Adrian Boucher, Certina Ho, Neil MacKinnon, Todd A. Boyle, Andrea Bishop, Paola Gonzalez, Christopher Hartt, James R. Barker
Oct 2018, 6 (4) E651-E656; DOI: 10.9778/cmajo.20180090
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