Article Figures & Tables
Figures
- Figure 1
Identification of priority research questions from the Child Health and Nutrition Research Initiative literature. Note: CHW = community health worker, IMCI = integrated management of childhood illness, PMTCT = Prevention of mother-to-child transmission of HIV.
Tables
Criterion Subquestions Answerable by research Would you say the research question is well framed?
Can a single study or a very small number of studies be designed to answer the research question?
Do you think that a study needed to answer the proposed research question would obtain ethical approval without major concerns?Research feasibility Is it likely that there will be sufficient capacity to carry out the proposed research?
Is it feasible to provide the training required for staff to carry out the research?
Is the cost and time required for this research reasonable?Deliverability Taking into account the level of difficulty with implementation of the potential delivery strategy (e.g., need for change of attitudes and beliefs, supervision, transport infrastructure), would you say that this strategy would be deliverable?
Taking into account the resources available to implement the intervention, would you say that the potential delivery strategy would be affordable?
Taking into account government capacity and partnership required, would you say that the potential delivery strategy would be sustainable?Impact Will the results of this research fill an important knowledge gap?
Are the results from this research likely to shape future planning and implementation?
Will the results of this research lead to a long-term reduction in disease burden?Effect on equity Would you say that the present distribution of the target disease burden/health issue affects mainly the poor and marginalized in the population?
Would you say that the poor and marginalized would be the most likely to benefit from the results of the proposed research?
Would you say that the proposed research has the overall potential to improve equity in disease burden distribution in the long-term (e.g., 10 yr)?- Table 2: Top 15 research questions according to their achieved RPS, with AEA related to each question
Rank Research question Criterion 1: answerable
by researchCriterion 2: research feasibility Criterion 3: deliverability Criterion 4: impact Criterion 5: equity RPS AEA 1 How can caregivers be mentored in recognizing child health danger signs (e.g., for pneumonia)? 0.90 0.97 0.91 0.89 0.80 89.25 0.82 2 Identify and evaluate delivery strategies to increase coverage of oral rehydration solution and zinc among remote populations and the poorest of the poor. 0.74 0.91 0.76 0.94 0.98 86.61 0.78 3 Can improved methods of detecting and managing dehydration in children with diarrhea reduce mortality? 0.93 0.88 0.88 0.85 0.77 86.26 0.82 4 Evaluate whether coverage of antibiotic treatment can be greatly expanded in safe and effective ways if administered by community health workers. 0.80 0.91 0.81 0.95 0.82 85.62 0.79 5 How can smart phoneintegrated community case management apps be implemented to accurately identify newborns and under-5 children requiring referral from their communities to a health facility? 0.88 0.93 0.85 0.90 0.66 84.23 0.78 6 What are effective delivery strategies to ensure that the most vulnerable individuals receive critical RMNCAH services? 0.70 0.85 0.68 0.95 0.99 83.31 0.77 7 Evaluate ways to reduce the financial barriers to facility births at the community level, such as through user fee exemptions, emergency loans, conditional cash transfers and transportation vouchers. 0.73 0.89 0.78 0.84 0.87 82.05 0.74 8 Can a simplified neonatal resuscitation program delivered by trained health workers reduce deaths due to intrapartum events and complications and birth asphyxia? 0.81 0.89 0.91 0.77 0.70 81.69 0.77 9 Can a standardized newborn kit (simple bag/mask, clean blades/knives, and cord clamps) with appropriate education reduce newborn mortality and morbidity? 0.78 0.93 0.82 0.66 0.90 81.54 0.72 10 How can mobile technology be used to identify mothers and children at risk, reduce unneeded transports and facilitate earlier timed care? 0.81 0.88 0.78 0.85 0.75 81.52 0.75 11 What factors drive care-seeking behaviour during childhood diarrheal disease, and how can we position oral rehydration solution and zinc to best respond to these factors? 0.62 0.81 0.88 0.88 0.88 81.32 0.71 12 Identify and evaluate strategies for retention and motivation of community health workers. 0.73 0.95 0.82 0.84 0.71 81.30 0.73 13 Identify innovative mechanisms to support and utilize existing trained but underutilized human resources in health (such as community midwives in Pakistan, auxiliary nurse midwives in India, and clinical officers in Malawi) to provide high-quality maternal health services in remote and rural areas. 0.64 0.84 0.74 0.88 0.93 80.62 0.72 14 How can we overcome the barriers to implementing kangaroo care in low-resource settings? 0.76 0.94 0.89 0.87 0.53 79.75 0.72 15 How can we overcome barriers to uptake of modern contraceptives in settings with very low prevalence of contraceptive use? 0.59 0.93 0.80 0.87 0.79 79.61 0.72 Note: AEA = average expert agreement, RMNCAH, reproductive, maternal, newborn, child and adolescent health, RPS = research priority score.
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