Skip to main content

Main menu

  • Home
  • Content
    • Current issue
    • Past issues
    • Collections
  • About
    • General information
    • Staff
    • Editorial board
    • Open access
    • Contact
  • CMAJ JOURNALS
    • CMAJ
    • CJS
    • JAMC
    • JPN

User menu

Search

  • Advanced search
CMAJ Open
  • CMAJ JOURNALS
    • CMAJ
    • CJS
    • JAMC
    • JPN
CMAJ Open

Advanced Search

  • Home
  • Content
    • Current issue
    • Past issues
    • Collections
  • About
    • General information
    • Staff
    • Editorial board
    • Open access
    • Contact
  • RSS feeds
Getting new auth cookie, if you see this message a lot, tell someone!
Research

Dipeptidyl peptidase-4 inhibitors and the risk of heart failure: a systematic review and meta-analysis

Subodh Verma, Ronald M. Goldenberg, Deepak L. Bhatt, Michael E. Farkouh, Adrian Quan, Hwee Teoh, Kim A. Connelly, Lawrence A. Leiter and Jan O. Friedrich
February 24, 2017 5 (1) E152-E177; DOI: https://doi.org/10.9778/cmajo.20160058
Subodh Verma
Divisions of Cardiac Surgery (Verma, Quan, Teoh), Endocrinology and Metabolism (Teoh, Leiter) and Cardiology (Connelly), and Departments of Surgery (Verma), Medicine (Connelly, Leiter, Friedrich) and Critical Care (Friedrich), Li Ka Shing Knowledge Institute of St. Michael's Hospital; Departments of Surgery (Verma), Medicine (Farkouh, Connelly, Leiter, Friedrich), Nutritional Sciences (Leiter) and Interdepartmental Division of Critical Care (Friedrich), University of Toronto, Toronto, Ont.; LMC Diabetes & Endocrinology (Goldenberg), Thornhill, Ont.; Brigham and Women's Hospital Heart & Vascular Center and Harvard Medical School (Bhatt), Boston, Mass.; Peter Munk Cardiac Centre (Farkouh), University Health Network, Toronto, Ont.
MDPhD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ronald M. Goldenberg
Divisions of Cardiac Surgery (Verma, Quan, Teoh), Endocrinology and Metabolism (Teoh, Leiter) and Cardiology (Connelly), and Departments of Surgery (Verma), Medicine (Connelly, Leiter, Friedrich) and Critical Care (Friedrich), Li Ka Shing Knowledge Institute of St. Michael's Hospital; Departments of Surgery (Verma), Medicine (Farkouh, Connelly, Leiter, Friedrich), Nutritional Sciences (Leiter) and Interdepartmental Division of Critical Care (Friedrich), University of Toronto, Toronto, Ont.; LMC Diabetes & Endocrinology (Goldenberg), Thornhill, Ont.; Brigham and Women's Hospital Heart & Vascular Center and Harvard Medical School (Bhatt), Boston, Mass.; Peter Munk Cardiac Centre (Farkouh), University Health Network, Toronto, Ont.
MD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Deepak L. Bhatt
Divisions of Cardiac Surgery (Verma, Quan, Teoh), Endocrinology and Metabolism (Teoh, Leiter) and Cardiology (Connelly), and Departments of Surgery (Verma), Medicine (Connelly, Leiter, Friedrich) and Critical Care (Friedrich), Li Ka Shing Knowledge Institute of St. Michael's Hospital; Departments of Surgery (Verma), Medicine (Farkouh, Connelly, Leiter, Friedrich), Nutritional Sciences (Leiter) and Interdepartmental Division of Critical Care (Friedrich), University of Toronto, Toronto, Ont.; LMC Diabetes & Endocrinology (Goldenberg), Thornhill, Ont.; Brigham and Women's Hospital Heart & Vascular Center and Harvard Medical School (Bhatt), Boston, Mass.; Peter Munk Cardiac Centre (Farkouh), University Health Network, Toronto, Ont.
MDMPH
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Michael E. Farkouh
Divisions of Cardiac Surgery (Verma, Quan, Teoh), Endocrinology and Metabolism (Teoh, Leiter) and Cardiology (Connelly), and Departments of Surgery (Verma), Medicine (Connelly, Leiter, Friedrich) and Critical Care (Friedrich), Li Ka Shing Knowledge Institute of St. Michael's Hospital; Departments of Surgery (Verma), Medicine (Farkouh, Connelly, Leiter, Friedrich), Nutritional Sciences (Leiter) and Interdepartmental Division of Critical Care (Friedrich), University of Toronto, Toronto, Ont.; LMC Diabetes & Endocrinology (Goldenberg), Thornhill, Ont.; Brigham and Women's Hospital Heart & Vascular Center and Harvard Medical School (Bhatt), Boston, Mass.; Peter Munk Cardiac Centre (Farkouh), University Health Network, Toronto, Ont.
MDMSc
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Adrian Quan
Divisions of Cardiac Surgery (Verma, Quan, Teoh), Endocrinology and Metabolism (Teoh, Leiter) and Cardiology (Connelly), and Departments of Surgery (Verma), Medicine (Connelly, Leiter, Friedrich) and Critical Care (Friedrich), Li Ka Shing Knowledge Institute of St. Michael's Hospital; Departments of Surgery (Verma), Medicine (Farkouh, Connelly, Leiter, Friedrich), Nutritional Sciences (Leiter) and Interdepartmental Division of Critical Care (Friedrich), University of Toronto, Toronto, Ont.; LMC Diabetes & Endocrinology (Goldenberg), Thornhill, Ont.; Brigham and Women's Hospital Heart & Vascular Center and Harvard Medical School (Bhatt), Boston, Mass.; Peter Munk Cardiac Centre (Farkouh), University Health Network, Toronto, Ont.
MPhil
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Hwee Teoh
Divisions of Cardiac Surgery (Verma, Quan, Teoh), Endocrinology and Metabolism (Teoh, Leiter) and Cardiology (Connelly), and Departments of Surgery (Verma), Medicine (Connelly, Leiter, Friedrich) and Critical Care (Friedrich), Li Ka Shing Knowledge Institute of St. Michael's Hospital; Departments of Surgery (Verma), Medicine (Farkouh, Connelly, Leiter, Friedrich), Nutritional Sciences (Leiter) and Interdepartmental Division of Critical Care (Friedrich), University of Toronto, Toronto, Ont.; LMC Diabetes & Endocrinology (Goldenberg), Thornhill, Ont.; Brigham and Women's Hospital Heart & Vascular Center and Harvard Medical School (Bhatt), Boston, Mass.; Peter Munk Cardiac Centre (Farkouh), University Health Network, Toronto, Ont.
PhD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Kim A. Connelly
Divisions of Cardiac Surgery (Verma, Quan, Teoh), Endocrinology and Metabolism (Teoh, Leiter) and Cardiology (Connelly), and Departments of Surgery (Verma), Medicine (Connelly, Leiter, Friedrich) and Critical Care (Friedrich), Li Ka Shing Knowledge Institute of St. Michael's Hospital; Departments of Surgery (Verma), Medicine (Farkouh, Connelly, Leiter, Friedrich), Nutritional Sciences (Leiter) and Interdepartmental Division of Critical Care (Friedrich), University of Toronto, Toronto, Ont.; LMC Diabetes & Endocrinology (Goldenberg), Thornhill, Ont.; Brigham and Women's Hospital Heart & Vascular Center and Harvard Medical School (Bhatt), Boston, Mass.; Peter Munk Cardiac Centre (Farkouh), University Health Network, Toronto, Ont.
MBBSPhD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Lawrence A. Leiter
Divisions of Cardiac Surgery (Verma, Quan, Teoh), Endocrinology and Metabolism (Teoh, Leiter) and Cardiology (Connelly), and Departments of Surgery (Verma), Medicine (Connelly, Leiter, Friedrich) and Critical Care (Friedrich), Li Ka Shing Knowledge Institute of St. Michael's Hospital; Departments of Surgery (Verma), Medicine (Farkouh, Connelly, Leiter, Friedrich), Nutritional Sciences (Leiter) and Interdepartmental Division of Critical Care (Friedrich), University of Toronto, Toronto, Ont.; LMC Diabetes & Endocrinology (Goldenberg), Thornhill, Ont.; Brigham and Women's Hospital Heart & Vascular Center and Harvard Medical School (Bhatt), Boston, Mass.; Peter Munk Cardiac Centre (Farkouh), University Health Network, Toronto, Ont.
MD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jan O. Friedrich
Divisions of Cardiac Surgery (Verma, Quan, Teoh), Endocrinology and Metabolism (Teoh, Leiter) and Cardiology (Connelly), and Departments of Surgery (Verma), Medicine (Connelly, Leiter, Friedrich) and Critical Care (Friedrich), Li Ka Shing Knowledge Institute of St. Michael's Hospital; Departments of Surgery (Verma), Medicine (Farkouh, Connelly, Leiter, Friedrich), Nutritional Sciences (Leiter) and Interdepartmental Division of Critical Care (Friedrich), University of Toronto, Toronto, Ont.; LMC Diabetes & Endocrinology (Goldenberg), Thornhill, Ont.; Brigham and Women's Hospital Heart & Vascular Center and Harvard Medical School (Bhatt), Boston, Mass.; Peter Munk Cardiac Centre (Farkouh), University Health Network, Toronto, Ont.
MDDPhil
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Tables
  • Related Content
  • Responses
  • Metrics
  • PDF
Loading

Article Information

vol. 5 no. 1 E152-E177
DOI 
https://doi.org/10.9778/cmajo.20160058
PubMed 
28459046
History 
  • Published online February 24, 2017.
Copyright & Usage 
Copyright 2017, Joule Inc. or its licensors

Author Information

  1. Subodh Verma, MD, PhD,
  2. Ronald M. Goldenberg, MD,
  3. Deepak L. Bhatt, MD, MPH,
  4. Michael E. Farkouh, MD, MSc,
  5. Adrian Quan, MPhil,
  6. Hwee Teoh, PhD,
  7. Kim A. Connelly, MBBS, PhD,
  8. Lawrence A. Leiter, MD,
  9. Jan O. Friedrich, MD, DPhil
  1. Affiliations: Divisions of Cardiac Surgery (Verma, Quan, Teoh), Endocrinology and Metabolism (Teoh, Leiter) and Cardiology (Connelly), and Departments of Surgery (Verma), Medicine (Connelly, Leiter, Friedrich) and Critical Care (Friedrich), Li Ka Shing Knowledge Institute of St. Michael's Hospital; Departments of Surgery (Verma), Medicine (Farkouh, Connelly, Leiter, Friedrich), Nutritional Sciences (Leiter) and Interdepartmental Division of Critical Care (Friedrich), University of Toronto, Toronto, Ont.; LMC Diabetes & Endocrinology (Goldenberg), Thornhill, Ont.; Brigham and Women's Hospital Heart & Vascular Center and Harvard Medical School (Bhatt), Boston, Mass.; Peter Munk Cardiac Centre (Farkouh), University Health Network, Toronto, Ont.
  1. Correspondence to:
    Jan Friedrich, j.friedrich{at}utoronto.ca
View Full Text

Usage statistics: February 2017 to August 2025

AbstractFullPdf
Feb 201725417
Mar 20173059124
Apr 2017573817
May 201742206144
Jun 2017277842
Jul 2017343536
Aug 2017165329
Sep 201782818
Oct 2017142917
Nov 2017102710
Dec 2017262210
Jan 2018302716
Feb 2018191910
Mar 2018271913
Apr 2018171224
May 2018491121
Jun 201834164
Jul 2018416311
Aug 2018287918
Sep 201832749
Oct 201832539
Nov 2018345539
Dec 2018195914
Jan 2019377030
Feb 2019355311
Mar 2019446915
Apr 2019286413
May 2019234714
Jun 2019294210
Jul 2019658
Aug 20197145
Sep 2019131713
Oct 201914913
Nov 20191586
Dec 201915134
Jan 202019711
Feb 2020846
Mar 202012813
Apr 20201654
May 20202106
Jun 20201459
Jul 2020944
Aug 202012104
Sep 2020945
Oct 202013114
Nov 202015911
Dec 20201949
Jan 20214411911
Feb 20211156
Mar 202121512
Apr 2021825
May 20211257
Jun 202119910
Jul 20212229
Aug 20213219
Sep 202132822
Oct 202111724
Nov 202122221
Dec 20218157
Jan 202221916
Feb 202251011
Mar 202272420
Apr 202283330
May 202292735
Jun 202233120
Jul 202232815
Aug 202283811
Sep 202263423
Oct 202274924
Nov 202253616
Dec 20225158
Jan 202331915
Feb 2023585
Mar 2023494
Apr 2023688
May 20231145
Jun 202321712
Jul 202382119
Aug 202311416
Sep 202341018
Oct 202382220
Nov 20233488
Dec 2023119411
Jan 202441612
Feb 20249145
Mar 202453032
Apr 20241310120
May 2024940510
Jun 20248287
Jul 202444214
Aug 202474430
Sep 202447321
Oct 202425423
Nov 202453222
Dec 202483124
Jan 202532324
Feb 202522327
Mar 202523448
Apr 202524636
May 202523520
Jun 202523928
Jul 20251239143
Aug 202575440
PreviousNext
Back to top

In this issue

CMAJ Open: 5 (1)
Vol. 5, Issue 1
1 Jan 2017
  • Table of Contents
  • Index by author

Article tools

Respond to this article
Print
Download PDF
Article Alerts
To sign up for email alerts or to access your current email alerts, enter your email address below:
Email Article

Thank you for your interest in spreading the word on CMAJ Open.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Dipeptidyl peptidase-4 inhibitors and the risk of heart failure: a systematic review and meta-analysis
(Your Name) has sent you a message from CMAJ Open
(Your Name) thought you would like to see the CMAJ Open web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Dipeptidyl peptidase-4 inhibitors and the risk of heart failure: a systematic review and meta-analysis
Subodh Verma, Ronald M. Goldenberg, Deepak L. Bhatt, Michael E. Farkouh, Adrian Quan, Hwee Teoh, Kim A. Connelly, Lawrence A. Leiter, Jan O. Friedrich
Feb 2017, 5 (1) E152-E177; DOI: 10.9778/cmajo.20160058

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Dipeptidyl peptidase-4 inhibitors and the risk of heart failure: a systematic review and meta-analysis
Subodh Verma, Ronald M. Goldenberg, Deepak L. Bhatt, Michael E. Farkouh, Adrian Quan, Hwee Teoh, Kim A. Connelly, Lawrence A. Leiter, Jan O. Friedrich
Feb 2017, 5 (1) E152-E177; DOI: 10.9778/cmajo.20160058
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like

Related Articles

  • PubMed
  • Google Scholar

Cited By...

  • Optimizing Management of Type 2 Diabetes and Its Complications in Patients With Heart Failure
  • Higher-Dose Sitagliptin and the Risk of Congestive Heart Failure in Older Adults with CKD
  • Google Scholar

Similar Articles

Collections

  • Clinical
    • Endocrinology & Metabolism
      • Diabetes
    • Cardiovascular Medicine
      • Heart failure

Content

  • Current issue
  • Past issues
  • Collections

About

  • General Information
  • Staff
  • Editorial Board
  • Advisory Panel
  • Contact Us
  • Reprints
  • Copyright and Permissions
CMAJ Group

Copyright 2025, CMA Impact Inc. or its licensors. All rights reserved. ISSN 2291-0026

All editorial matter in CMAJ OPEN represents the opinions of the authors and not necessarily those of the Canadian Medical Association or its subsidiaries.

To receive any of these resources in an accessible format, please contact us at CMAJ Group, 500-1410 Blair Towers Place, Ottawa ON, K1J 9B9; p: 1-888-855-2555; e: [email protected].

CMA Civility, Accessibility, Privacy

 

 

Powered by HighWire