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Research

Acceptability and yield of birth-cohort screening for hepatitis C virus in a Canadian population being screened for colorectal cancer: a cross-sectional study

Robert P. Myers, Pam Crotty, Susanna Town, Janine English, Kevin Fonseca, Raymond Tellier, Mark G. Swain, S. Elizabeth McGregor, Steven J. Heitman and Robert J. Hilsden
February 06, 2015 3 (1) E62-E67; DOI: https://doi.org/10.9778/cmajo.20140024
Robert P. Myers
1Liver Unit, Division of Gastroenterology and Hepatology, Department of Medicine, University of Calgary, Calgary, Alta.
2Department of Community Health Sciences, University of Calgary, Calgary, Alta.
MDMSc
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Pam Crotty
1Liver Unit, Division of Gastroenterology and Hepatology, Department of Medicine, University of Calgary, Calgary, Alta.
MSc
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Susanna Town
3Forzani & MacPhail Colon Cancer Screening Centre, Alberta Health Services, Calgary, Alta.
PhD
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Janine English
3Forzani & MacPhail Colon Cancer Screening Centre, Alberta Health Services, Calgary, Alta.
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Kevin Fonseca
4Provincial Laboratory for Public Health, Calgary, Alta.
PhD
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Raymond Tellier
4Provincial Laboratory for Public Health, Calgary, Alta.
MDMSc
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Mark G. Swain
1Liver Unit, Division of Gastroenterology and Hepatology, Department of Medicine, University of Calgary, Calgary, Alta.
MDMSc
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S. Elizabeth McGregor
3Forzani & MacPhail Colon Cancer Screening Centre, Alberta Health Services, Calgary, Alta.
PhD
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Steven J. Heitman
3Forzani & MacPhail Colon Cancer Screening Centre, Alberta Health Services, Calgary, Alta.
MDMSc
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Robert J. Hilsden
2Department of Community Health Sciences, University of Calgary, Calgary, Alta.
3Forzani & MacPhail Colon Cancer Screening Centre, Alberta Health Services, Calgary, Alta.
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    Figure 1:

    Flow diagram of participant recruitment in a colorectal cancer screening population to determine the acceptability of screening for hepatitis C virus (HCV). A convenience sample of attendees at an education session about screening for colorectal cancer completed a survey regarding their willingness to undergo screening for HCV.

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    Table 1: Characteristics of patients referred for colorectal cancer screening by willingness to undergo screening for HCV
    Variable*Total cohort, no. (%)†
    n = 1012
    Patients willing to be screened, no. (%)†
    n = 903‡
    Patients unwilling to be screened, no. (%)†
    n = 100‡
    Unadjusted OR for willingness to be screened
    (95% CI)‡
    Male529 (52.3)474 (52.5)51 (51.0)1.09 (0.74–1.59)
    Age, yr, median (IQR)56 (53–62)56 (53–62)57 (53–61)0.99 (0.96–1.02)
    Baby boomer (born 1945–1965)914 (90.5)814 (90.2)91 (91.9)0.81 (0.38–1.73)
    White876 (87.1)803 (89.3)65 (66.3)4.25 (2.66–6.79)
    Born outside of Canada221 (21.9)177 (19.6)42 (42.0)0.34 (0.22–0.52)
    University education399 (42.3)358 (42.2)38 (43.7)0.94 (0.60–1.47)
    Married or common-law831 (82.5)741 (82.4)83 (83.8)0.90 (0.52–1.59)
    HCV risk factors
        0746 (73.7)653 (72.3)89 (89.0)Ref
        1169 (16.7)158 (17.5)8 (8.0)2.69 (1.28–5.66)
        ≥ 297 (9.6)92 (10.2)3 (3.0)4.18 (1.30–13.5)

    Note: CI = confidence interval, HCV = hepatitis C virus, IQR = interquartile range, OR = odds ratio.
*Number of respondents missing for the following variables: sex (n = 1), age (n = 2), race (n = 6), immigration status (n =1), marital status (n = 5) and education level (n = 69).
†Unless otherwise specified.
‡Excludes 9 patients with a self-reported diagnosis of HCV.

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    Acceptability and yield of birth-cohort screening for hepatitis C virus in a Canadian population being screened for colorectal cancer: a cross-sectional study
    Robert P. Myers, Pam Crotty, Susanna Town, Janine English, Kevin Fonseca, Raymond Tellier, Mark G. Swain, S. Elizabeth McGregor, Steven J. Heitman, Robert J. Hilsden
    Jan 2015, 3 (1) E62-E67; DOI: 10.9778/cmajo.20140024

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    Acceptability and yield of birth-cohort screening for hepatitis C virus in a Canadian population being screened for colorectal cancer: a cross-sectional study
    Robert P. Myers, Pam Crotty, Susanna Town, Janine English, Kevin Fonseca, Raymond Tellier, Mark G. Swain, S. Elizabeth McGregor, Steven J. Heitman, Robert J. Hilsden
    Jan 2015, 3 (1) E62-E67; DOI: 10.9778/cmajo.20140024
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