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The impact of poisoning in British Columbia: a cost analysis

Fahra Rajabali, Kate Turcotte, Alex Zheng, Roy Purssell, Jane A. Buxton and Ian Pike
February 14, 2023 11 (1) E160-E168; DOI: https://doi.org/10.9778/cmajo.20220089
Fahra Rajabali
BC Injury Research and Prevention Unit (Rajabali, Turcotte, Zheng, Pike), BC Children’s Hospital; Department of Emergency Medicine (Purssell), University of British Columbia; BC Drug and Poison Information Centre (Purssell, Buxton); School of Population and Public Health (Buxton), University of British Columbia; Department of Pediatrics (Pike), University of British Columbia, Vancouver, BC
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Kate Turcotte
BC Injury Research and Prevention Unit (Rajabali, Turcotte, Zheng, Pike), BC Children’s Hospital; Department of Emergency Medicine (Purssell), University of British Columbia; BC Drug and Poison Information Centre (Purssell, Buxton); School of Population and Public Health (Buxton), University of British Columbia; Department of Pediatrics (Pike), University of British Columbia, Vancouver, BC
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Alex Zheng
BC Injury Research and Prevention Unit (Rajabali, Turcotte, Zheng, Pike), BC Children’s Hospital; Department of Emergency Medicine (Purssell), University of British Columbia; BC Drug and Poison Information Centre (Purssell, Buxton); School of Population and Public Health (Buxton), University of British Columbia; Department of Pediatrics (Pike), University of British Columbia, Vancouver, BC
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Roy Purssell
BC Injury Research and Prevention Unit (Rajabali, Turcotte, Zheng, Pike), BC Children’s Hospital; Department of Emergency Medicine (Purssell), University of British Columbia; BC Drug and Poison Information Centre (Purssell, Buxton); School of Population and Public Health (Buxton), University of British Columbia; Department of Pediatrics (Pike), University of British Columbia, Vancouver, BC
MD
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Jane A. Buxton
BC Injury Research and Prevention Unit (Rajabali, Turcotte, Zheng, Pike), BC Children’s Hospital; Department of Emergency Medicine (Purssell), University of British Columbia; BC Drug and Poison Information Centre (Purssell, Buxton); School of Population and Public Health (Buxton), University of British Columbia; Department of Pediatrics (Pike), University of British Columbia, Vancouver, BC
MBBS MHSc
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Ian Pike
BC Injury Research and Prevention Unit (Rajabali, Turcotte, Zheng, Pike), BC Children’s Hospital; Department of Emergency Medicine (Purssell), University of British Columbia; BC Drug and Poison Information Centre (Purssell, Buxton); School of Population and Public Health (Buxton), University of British Columbia; Department of Pediatrics (Pike), University of British Columbia, Vancouver, BC
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Article Figures & Tables

Tables

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    Table 1:

    Direct and indirect cost components of poisoning in British Columbia by patient disposition

    DeathHospital admissionEDAmbulanceBC DPIC
    Direct cost components
    Ambulance service (attendance and transportation, pharmaceuticals, medical supplies)Calls to BC DPIC and transferred to hospitalCalls to BC DPIC and seen in EDCalls to BC DPIC and attended by ambulanceCalls to BC DPIC and not attended by ambulance, seen in ED or transferred to hospital
    ED treatment (physician care, pharmaceuticals, medical supplies)Ambulance service (attendance and transportation, pharmaceuticals, medical supplies)Ambulance service (attendance and transportation, pharmaceuticals, medical supplies)Ambulance service (attendance, pharmaceuticals, medical supplies)
    Hospital care (physician care, pharmaceuticals, medical supplies)ED treatment (physician care, pharmaceuticals, medical supplies)ED treatment (physician care, pharmaceuticals, medical supplies)
    Coroner service and autopsyHospital care (physician care, pharmaceuticals, medical supplies)Long-term medical care
    Funeral costLong-term medical careLong-term rehabilitation
    Long-term rehabilitation
    Indirect cost components
    DeathsHospital admission
    Future income forgone from potential years of life lost and premature deathTime away from work due to hospital admission Years of disability resulting in forgone income
    • Note: BC DPIC = British Columbia Drug and Poison Information Centre, ED = emergency department.

    • View popup
    Table 2:

    Incidence of poisoning and characteristics of patients in British Columbia by patient disposition, 2016

    CharacteristicPatient disposition, no. (%)
    Deaths n = 1224 (3%)Hospital admission*
    n = 4657 (10%)
    ED†
    n = 13 764 (30%)
    Ambulance‡
    n = 4135 (9%)
    BC DPIC§
    n = 21 411 (47%)
    Total¶
    n = 45 191 (100%)
    Sex
     Male920 (75)1921 (41)9256 (67)2090 (51)10 221 (48)24 408 (54)
     Female304 (25)2736 (59)4508 (33)1136 (27)10 974 (51)19 658 (43)
    Age group, yr
     < 150237 (5)581 (4)94 (2)11 885 (56)12 797 (28)
     15–24127 (10)1074 (23)2772 (20)543 (13)1200 (6)5716 (13)
     25–641031 (84)2765 (59)8668 (63)2118 (51)2642 (12)17 224 (38)
     65–7447 (4)317 (7)941 (7)264 (6)484 (2)2053 (5)
     > 7519 (2)264 (6)803 (6)206 (5)526 (2)1818 (4)
    • Note: BC DPIC = British Columbia Drug and Poison Information Centre, ED = emergency department.

    • ↵* Excludes in-hospital deaths.

    • ↵† Excludes patients admitted to the hospital.

    • ↵‡ Patients not transported to the hospital. There were 909 (22%) ambulance patients with missing information on sex and 910 (23%) for age group.

    • ↵§ Patients who had called the BC DPIC and who were not seen by the ambulance or transferred to the hospital. There were 218 (1%) BC DPIC patients with missing information on sex and 4674 (22%) for age group.

    • ↵¶ There were 1125 (3%) of all patients with missing information on sex and 5583 (12%) with missing information on age.

    • View popup
    Table 3:

    Poisoning in British Columbia by patient disposition, age group (years) and sex, 2016 (rate per 100 000 population)

    Age group and sexPatient disposition rate per 100 000 population
    DeathsHospital admissionEDAmbulanceBC DPIC
    Total25.295.8283.385.1440.6
     < 15033.782.613.41690.2
     15–2421.6182.3470.392.2203.6
     25–6437.9101.6318.577.894.8
     65–749.664.7192.253.9111.1
     > 755.374.2225.558.0148.3
    Males38.279.9384.886.9346.4
     < 15016.780.311.01754.2
     15–2428.6102.7494.793.8163.1
     25–6458.696.6465.6108.783.0
     65–7413.855.3266.670.090.5
     > 757.774.0356.886.3115.5
    Females12.4111.5183.746.3339.7
     < 15051.685.015.91614.2
     15–2413.9269.2443.690.5245.8
     25–6417.7106.5175.447.8103.7
     65–745.673.7121.438.5130.3
     > 753.574.2122.335.7175.1
    • Note: BC DPIC = British Columbia Drug and Poison Information Centre, ED = emergency department.

    • View popup
    Table 4:

    Costs of poisoning in British Columbia by patient disposition and intent, 2016

    Patient dispositionIntent, cost, $Total costs, $Average cost per case, $
    UnintentionalSuicide or self-harmViolenceUndetermined
    Direct costs*
    Total50 602 08349 065 296104 8809 098 550108 870 8092409
     Deaths10 477 7411 637 9340659 36112 775 03610 437
     Hospital admission26 781 47634 494 49454 9725 869 14767 200 09014 430
     ED11 594 16211 817 65388062 383 39525 804 0151875
     Ambulance873 1341 070 2413751184 4952 131 621516
     BC DPIC875 57044 97337 3512152960 04745
    Indirect costs*
    Total629 238 92666 669 58117117 704 320703 614 53815 570
     Deaths628 747 12165 677 57407 585 509702 010 205573 538
     Hospital admission491 805992 0071711118 8111 604 333344
    Total costs*679 841 009115 734 877106 59116 802 870812 485 34717 979
     Deaths639 224 86267 315 50808 244 870714 785 241583 975
     Hospital admission27 273 28135 486 50156 6835 987 95868 804 42314 774
     ED11 594 16211 817 65388062 383 39525 804 0151875
     Ambulance873 1341 070 2413751184 4952 131 621516
     BC DPIC875 57044 97337 3512152960 04745
    • Note: BC DPIC = British Columbia Drug and Poison Information Centre, ED = emergency department.

    • ↵* Bolded values are total values for direct costs, indirect costs and total costs.

    • View popup
    Table 5:

    Costs of poisonings in British Columbia by patient disposition, age group (years) and sex, 2016

    Age group (population) and sexPatient disposition, cost, $Total direct costs, $Per capita cost, $
    DeathsHospital admissionEDAmbulanceBC DPIC
    Direct costs*
    Total* (4 859 250)12 498 16767 174 80125 801 8202 125 344750 654108 350 78522.30
     < 15 (703 176)02 051 030784 02171 172531 5633 437 7864.89
     15–24 (589 297)1 186 42511 344 9134 401 531357 78954 11917 344 77729.43
     25–64 (2 721 148)10 456 16241 992 98716 577 5421 387 134116 29170 530 11625.92
     65–74 (489 618)608 7355 980 9872 175 265172 65324 6518 962 29218.30
     > 75 (356 011)246 8455 804 8841 863 461136 59524 0308 075 81622.68
    Male (2 405 364)9 303 54631 279 61318 312 2761 371 506375 99060 642 93125.21
     < 15 (360 168)0512 236359 62531 324283 2811 186 4673.29
     15–24 (307 750)844 5373 647 0822 488 168189 14622 8347 191 76623.37
     25–64 (1 342 218)7 949 24222 027 02512 657 557953 49651 67743 638 99732.51
     65–74 (238 563)361 3782 900 3531 582 795108 84799124 963 28520.80
     > 75 (156 665)148 3892 192 9171 224 13188 69382863 662 41623.38
    Female (2 453 886)3 194 62135 895 1877 489 544753 837374 66447 707 85419.44
     < 15 (343 008)01 538 794424 39639 847248 2822 251 3196.56
     15–24 (281 547)341 8897 697 8311 913 363168 64331 28510 153 01136.06
     25–64 (1 378 930)2 506 92019 965 9613 919 985433 63864 61426 891 11819.50
     65–74 (251 055)247 3573 080 634592 47063 80614 7393 999 00715.93
     > 75 (199 346)98 4553 611 967639 33047 90315 7444 413 39922.14
    Indirect costs*
    Total (4 859 250)702 010 2051 604 333N/AN/AN/A703 614 538144.80
     15–24 (589 297)143 391 615341 970143 733 584243.91
     25–64 (2 721 148)558 618 5901 262 364559 880 954205.75
    Male (2 405 364)525 000 709697 236525 697 944218.55
     15–24 (307 750)98 586 712100 69498 687 406320.67
     25–64 (1 342 218)426 413 997596 542427 010 538318.14
    Female (2 453 886)177 009 496907 098177 916 59472.50
     15–24 (281 547)44 804 902241 27645 046 178160.00
     25–64 (1 378 930)132 204 594665 822132 870 41696.36
    • Note: BC DPIC = British Columbia Drug and Poison Information Centre, ED = emergency department, N/A = not applicable.

    • ↵* Bolded values are total values for direct costs, indirect costs and total costs.

    • View popup
    Table 6:

    Sensitivity analysis, effects of changes in discount rate, unemployment rate and participation rate in economic costs of poisoning (Can$ million), British Columbia, 2016

    Key driverDirect costsIndirect costsTotal costs
    Discount rate
     1%$108.87$746.06$854.93
     1.5% (base case)$108.87$703.61$812.49
     3%$108.87$597.97$706.84
     5%$108.87$494.02$602.89
     change (1.5–1.0), %06.05.2
     change (1.5–3.0), %0−15.0−13.0
     change (1.5–5.0), %0−29.8−25.8
    Unemployment rate
     4%$108.87$718.59$827.46
     6% (base case)$108.87$703.61$812.49
     8%$108.87$688.64$797.51
     change (6.0–4.0), %02.11.8
     change (6.0–8.0), %0−2.1−1.8
    Participation rate
     54.4%$108.87$594.36$703.23
     64.4% (base case)$108.87$703.61$812.49
     74.4%$108.87$812.87$921.74
     change (64.4–54.4), %0−15.5−13.4
     change (64.4–74.4), %015.513.4
    • * Bolded values are the key drivers (base case) that were used to calculate the costs in this study. This table is showing the sensitivity of what the costs would have been using key driver values below or above the base case values.

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The impact of poisoning in British Columbia: a cost analysis
Fahra Rajabali, Kate Turcotte, Alex Zheng, Roy Purssell, Jane A. Buxton, Ian Pike
Jan 2023, 11 (1) E160-E168; DOI: 10.9778/cmajo.20220089

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The impact of poisoning in British Columbia: a cost analysis
Fahra Rajabali, Kate Turcotte, Alex Zheng, Roy Purssell, Jane A. Buxton, Ian Pike
Jan 2023, 11 (1) E160-E168; DOI: 10.9778/cmajo.20220089
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