The impact of shifting demographics, variants of concern and vaccination on outcomes during the first 3 COVID-19 waves in Alberta and Ontario: a retrospective cohort study

The Department of Medicine, Faculty of Medicine and Dentistry (McAlister, Saxinger, Bakal), University of Alberta, Edmonton, Alta.; The Alberta Strategy for Patient Oriented Research Support Unit (McAlister, Nabipoor, Bakal); The Canadian VIGOUR Centre (McAlister), University of Alberta, Edmonton, Alta.; ICES (Chu, Lee); University of Toronto (Chu, Lee); University Health Network (Lee), Toronto, Ont.

The Department of Medicine, Faculty of Medicine and Dentistry (McAlister, Saxinger, Bakal), University of Alberta, Edmonton, Alta.; The Alberta Strategy for Patient Oriented Research Support Unit (McAlister, Nabipoor, Bakal); The Canadian VIGOUR Centre (McAlister), University of Alberta, Edmonton, Alta.; ICES (Chu, Lee); University of Toronto (Chu, Lee); University Health Network (Lee), Toronto, Ont.

The Department of Medicine, Faculty of Medicine and Dentistry (McAlister, Saxinger, Bakal), University of Alberta, Edmonton, Alta.; The Alberta Strategy for Patient Oriented Research Support Unit (McAlister, Nabipoor, Bakal); The Canadian VIGOUR Centre (McAlister), University of Alberta, Edmonton, Alta.; ICES (Chu, Lee); University of Toronto (Chu, Lee); University Health Network (Lee), Toronto, Ont.

The Department of Medicine, Faculty of Medicine and Dentistry (McAlister, Saxinger, Bakal), University of Alberta, Edmonton, Alta.; The Alberta Strategy for Patient Oriented Research Support Unit (McAlister, Nabipoor, Bakal); The Canadian VIGOUR Centre (McAlister), University of Alberta, Edmonton, Alta.; ICES (Chu, Lee); University of Toronto (Chu, Lee); University Health Network (Lee), Toronto, Ont.

The Department of Medicine, Faculty of Medicine and Dentistry (McAlister, Saxinger, Bakal), University of Alberta, Edmonton, Alta.; The Alberta Strategy for Patient Oriented Research Support Unit (McAlister, Nabipoor, Bakal); The Canadian VIGOUR Centre (McAlister), University of Alberta, Edmonton, Alta.; ICES (Chu, Lee); University of Toronto (Chu, Lee); University Health Network (Lee), Toronto, Ont.

The Department of Medicine, Faculty of Medicine and Dentistry (McAlister, Saxinger, Bakal), University of Alberta, Edmonton, Alta.; The Alberta Strategy for Patient Oriented Research Support Unit (McAlister, Nabipoor, Bakal); The Canadian VIGOUR Centre (McAlister), University of Alberta, Edmonton, Alta.; ICES (Chu, Lee); University of Toronto (Chu, Lee); University Health Network (Lee), Toronto, Ont.