Unadjusted and adjusted odds ratios of cardiovascular disease incidence per mmol/L increase of nonfasting remnant cholesterol and low-density lipoprotein cholesterol
| Variable | No. (%) n = 13 988 | Unadjusted OR (95% CI) | Adjusted* OR (95% CI) |
|---|---|---|---|
| Remnant cholesterol | |||
| CVD composite | 1156 (8.3) | 1.81 (1.56–2.09) | 1.48 (1.27–1.73) |
| Ischemic heart disease | 1056 (7.6) | 1.83 (1.57–2.13) | 1.49 (1.27–1.75) |
| Acute coronary syndrome† | 153 (1.1) | 2.18 (1.51–3.15) | 1.42 (0.97–2.08) |
| Heart failure | 168 (1.2) | 1.95 (1.36–2.79) | 1.47 (1.01–2.14) |
| Stroke‡ | 53 (0.4) | 1.75 (0.92–3.33) | 1.12 (0.58–2.17) |
| LDL cholesterol | |||
| CVD composite | 1156 (8.3) | 0.76 (0.71–0.82) | 0.73 (0.68–0.79) |
| Ischemic heart disease | 1056 (7.6) | 0.77 (0.71–0.83) | 0.74 (0.69–0.81) |
| Acute coronary syndrome† | 153 (1.1) | 0.51 (0.41–0.62) | 0.55 (0.44–0.68) |
| Heart failure | 168 (1.2) | 0.64 (0.53–0.77) | 0.64 (0.53–0.78) |
| Stroke‡ | 53 (0.4) | 0.46 (0.33–0.65) | 0.47 (0.33–0.69) |
Note: CI = confidence interval, CVD = cardiovascular disease, LDL = low-density lipoprotein, OR = odds ratio.
↵* Adjusted model included age, sex, statin use, Elixhauser Comorbidity Index, remnant cholesterol and LDL cholesterol.
↵† Aggregate of myocardial infarction and angina.
↵‡ Aggregate of transient ischemic attack and acute ischemic stroke.