Table 2:

Interrupted time series analyses

LocationPreintervention period*Postintervention period*Absolute level change at time of intervention, visits or deaths per month (95% CI)Slope change, change in visits or deaths per month ± SESlope change significance, p value
SCS site analysis
ED visits
 CalgaryOctober 2013–October 2017October 2017–February 2020−22.7 (−29.7 to −15.8)−0.2 ± 0.40.5
 EdmontonOctober 2013–March 2018March 2018–February 20200.7 (−11.4 to 12.8)−1.0 ± 0.60.07
 Red Deer†October 2013–October 2018October 2018–February 2020−1.4 (−4.5 to 1.7)0.01 ± 0.2> 0.9
 LethbridgeOctober 2013–March 2018March 2018–February 2020−8.8 (−11.7 to −5.9)−0.9 ± 0.2< 0.001
Deaths
 CalgaryOctober 2013–October 2017October 2017–March 2019−1.7 (−4.5 to 0.9)−0.3 ± 0.20.09
 EdmontonOctober 2013–March 2019March 2018–March 2019−5.9 (−8.9 to −2.9)−1.4 ± 0.2< 0.001
 Red Deer†October 2013–March 2019October 2018–March 2019−0.1 (−0.5 to 0.3)−0.1 ± 0.10.09
 LethbridgeOctober 2013–March 2018March 2018–March 20190.03 (−0.4 to 0.7)−0.01 ± 0.030.6
CBN program analysis
ED visits
 Urban AlbertaOctober 2013–January 2016January 2016–February 202038.9 (33.3 to 44.4)−1.9 ± 0.4< 0.001
 Rural AlbertaOctober 2013–January 2016January 2016–February 20203.7 (−0.3 to 7.1)−1.1 ± 0.2< 0.001
Deaths
 Urban AlbertaOctober 2013–January 2016January 2016–March 20199.1 (6.7 to 11.5)−0.5 ± 0.20.004
 Rural AlbertaOctober 2013–January 2016January 2016–March 20192.6 (2.6 to 4.7)−0.1 ± 0.10.2

  • Note: CBN = community-based naloxone, ED = emergency department, SCS = safe consumption site, SE = standard error.

  • ↵* All periods are defined as the first date of the indicated month.

  • ↵† OPS site.