Table 2:

Coding hierarchy

Major theme; subthemeFactor
Access
Authorization burden

  • Supply and quality

  • Clinician

  • Financial

Law and policy burden

  • Federal

  • Provincial

  • Hospital policy

Patient burden

  • Pragmatic use

  • Conditional rights

Relationships and relational autonomy
Clinical communication

  • Individualistic approach

  • Data transparency

  • Informed consent

Clinical support

  • Support and guide use

  • Responsibility to educate

  • Referrals

Nonclinical communication

  • Misconceptions, misperceptions

  • Public promotion of information

Medically appropriate use
Risk–benefit calculus

  • Harms

  • Balance risk and benefit

Evidence­based treatment

  • Considered option

  • Not considered option

Consumption

  • Various forms, routes, dosages

  • Recommendations

Research priorities
Necessary research

  • Data from any scientific method

  • Appropriate use

  • Adverse effects

  • Efficacy

  • Safety

  • Dosing

  • Randomized controlled clinical trials

Barriers to research

  • Study design

  • Institutional

Research ethics

  • Ethical considerations

  • Obligations