Table 4:

Predictors of admission to hospital within 6 months for outpatients with CDI*

CovariateAdjusted HR (95% CI)
Recurrence (Ref: No recurrence)1.58 (1.31 to 1.91)
Age, yr (Ref: 18–69 yr)
 70–791.55 (1.25 to 1.92)
 ≥ 801.49 (1.23 to 1.81)
Male sex (v. female)0.95 (0.81 to 1.11)
SEFI1.17 (1.07 to 1.27)
CCI (Ref: 0)§
 11.54 (1.2 to 1.96)
 21.35 (1.03 to 1.76)
 ≥ 31.83 (1.43 to 2.36)
CDI subtype (v. community-associated)
 Community-onset HCF-associated1.46 (1.21 to 1.77)
 Indeterminate1.31 (1.05 to 1.63)
Ambulatory care visits in previous year (v. least)
 Quartile 21.34 (0.99 to 1.82)
 Quartile 31.84 (1.36 to 2.48)
 Most2.20 (1.6 to 3.02)
  • Note: CDI = Clostridioides difficile infection, CCI = Charlson Comorbidity Index, CI = confidence interval, HCF = health care facility, HR = hazard ratio, SEFI = Socioeconomic Factor Index.

  • * 307 admissions among 2530 outpatients diagnosed with CDI.

  • The HRs were adjusted for all the factors listed in the table.

  • SEFI was handled as a continuous variable.

  • § Renal disease and diabetes omitted from CCI calculation.